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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MEF2D
All Species:
18.79
Human Site:
S450
Identified Species:
34.44
UniProt:
Q14814
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14814
NP_005911.1
521
55938
S450
V
S
P
S
R
E
R
S
P
A
P
P
P
P
A
Chimpanzee
Pan troglodytes
XP_001165500
521
55889
S450
V
S
P
S
R
E
R
S
P
A
P
P
P
P
A
Rhesus Macaque
Macaca mulatta
XP_001103222
500
53974
Q431
P
P
P
Q
P
Q
P
Q
P
Q
P
P
Q
P
Q
Dog
Lupus familis
XP_547534
525
56508
G432
P
A
T
R
P
E
P
G
D
G
L
S
S
P
A
Cat
Felis silvestris
Mouse
Mus musculus
Q63943
514
54974
S443
V
S
P
S
R
E
R
S
P
A
P
P
P
P
A
Rat
Rattus norvegicus
O89038
507
54350
S436
V
S
P
S
R
E
R
S
P
A
P
P
P
P
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507540
505
54598
Q434
Q
Q
Q
Q
Q
Q
Q
Q
Q
Q
Q
P
Q
Q
Q
Chicken
Gallus gallus
Q9W6U8
499
53650
Q435
Q
P
P
Q
P
P
Q
Q
P
P
Q
R
Q
E
M
Frog
Xenopus laevis
Q03413
498
54053
S424
A
S
P
N
R
E
R
S
T
G
T
P
L
S
C
Zebra Danio
Brachydanio rerio
NP_571392
529
57466
S435
V
S
P
N
R
D
R
S
T
P
S
S
T
P
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40791
539
57097
Q447
S
V
L
S
H
A
Q
Q
H
H
L
G
M
P
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38847
268
30310
N204
D
S
K
C
S
L
Q
N
T
D
S
D
T
T
L
Baker's Yeast
Sacchar. cerevisiae
Q12224
676
73465
N544
A
K
P
G
N
T
N
N
P
G
T
F
P
P
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
53.7
72.5
N.A.
96.1
94.4
N.A.
54.1
54.7
73.6
70.1
N.A.
28
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
63.9
75.8
N.A.
97.1
95.5
N.A.
64.8
64.3
82.5
78.2
N.A.
39.5
N.A.
N.A.
N.A.
P-Site Identity:
100
100
33.3
20
N.A.
100
100
N.A.
6.6
13.3
46.6
46.6
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
40
26.6
N.A.
100
100
N.A.
26.6
20
53.3
60
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.2
22.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34.9
38.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
8
0
0
0
8
0
0
0
31
0
0
0
0
39
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
8
0
0
0
0
8
0
0
8
8
0
8
0
0
0
% D
% Glu:
0
0
0
0
0
47
0
0
0
0
0
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
0
0
8
0
0
0
8
0
24
0
8
0
0
8
% G
% His:
0
0
0
0
8
0
0
0
8
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
8
0
0
8
0
0
0
0
16
0
8
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% M
% Asn:
0
0
0
16
8
0
8
16
0
0
0
0
0
0
8
% N
% Pro:
16
16
70
0
24
8
16
0
54
16
39
54
39
70
0
% P
% Gln:
16
8
8
24
8
16
31
31
8
16
16
0
24
8
16
% Q
% Arg:
0
0
0
8
47
0
47
0
0
0
0
8
0
0
0
% R
% Ser:
8
54
0
39
8
0
0
47
0
0
16
16
8
8
0
% S
% Thr:
0
0
8
0
0
8
0
0
24
0
16
0
16
8
0
% T
% Val:
39
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _